联系方式
邮箱:lrjuan@hit.edu.cn
个人简介
教育经历:
2003.9-2007.7哈尔滨工业大学计算机科学与技术专业本科
2007.9-2009.7哈尔滨工业大学计算机科学与技术专业硕士
2009.9-2015.3哈尔滨工业大学计算机科学与技术专业博士
工作经历:
2015.5-2020.12哈尔滨工业大学生命科学与技术学院讲师
2020.12-至今哈尔滨工业大学生命科学与技术学院副教授
Personal Profile
EDUCATION:
B.Eng.Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2003-2007
M.Eng.Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2007-2009
Ph.D. Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2009-2015
ACADEMIC APPOINTMENTS:
Lecturer, Harbin Institute of Technology, Harbin, China, Biomedical Engineering, 2015-2020
Associate Professor, Harbin Institute of Technology, Harbin, China, Biomedical Engineering, 2020-present
研究方向和领域
生物信息学
Bioinformatics
研究内容
主要研究方向为基因组大数据分析方法与软件,包括三方面内容:
1.基因组学机器学习,研究机器学习算法在基因组学问题上的应用与改进;
2.基因组注释与可视化,研究对容量庞大、格式多样、关系复杂的基因组大数据进行注释及可视化方法与软件;
3.多组学数据分析,运用统计、计算方法,分析多组学数据、解决生物学问题。
Research Interests
The majorresearch area is methods and software of genome bigdata analysis, including 3 topics:
1. Machine learning in genomics: Improvement and application of machine learning algorithm for genomics.
2. Genome annotation and visualization: Annotation and visualization methods/software for genome bigdata with mass volume, various formats and complex relationship.
3. Multi-omics data analysis, Analyzing multi-omics data by computational and statistical methods, solving biological problem.
研究成果
代表性论文
1.Juan, L.*, Wang, Y., Jiang, J., Yang, Q.,Wang, G., and Wang, Y.* (2020). Evaluating Individual Genome Similarity with a Topic Model.Bioinformatics.(SCI检索)
2.Juan, L.*, Wang, Y., Jiang, J., Yang, Q.,Jiang, Q., and Wang, Y.* (2020). PGsim: A Comprehensive and Highly Customizable Personal Genome Simulator.Front Bioeng Biotechnol8, 28.(SCI检索)
3.Juan, L., Liu, Y., Wang, Y., Teng, M.,Zang, T., and Wang, Y. (2015). Family genome browser: visualizing genomes with pedigree information.Bioinformatics31, 2262-2268.(SCI检索)
4.Juan, L., Teng, M., Zang, T., Hao, Y.,Wang, Z., Yan, C., Liu, Y., Li, J., Zhang, T., and Wang, Y. (2014). The personal genome browser: visualizing functions of genetic variants.Nucleic Acids Res42, W192-197.(SCI检索)
5.Juan, L., Wang, G., Radovich, M.,Schneider, B.P., Clare, S.E., Wang, Y., and Liu, Y. (2013). Potential roles of microRNAs in regulating long intergenic noncoding RNAs.BMC Medical Genomics6 Suppl 1,S7.(SCI检索)
获奖
2019年度黑龙江省科学技术一等奖(排名4)
开设的课程
生物信息学
Bioinformatics
生物数据库及软件应用基础
Foundation of Biological Database and Software
基因组信息学
Genome Informatics